The London Thames Gateway Development Committee has granted planning permission for the Unex Group’s 26-storey tower of residential flats and city offices.
Designed by Allies and Morrison Architects, the building will replace Station House, which is to be demolished, and feature ground floor retail space, five floors of new offices and 260 flats.
Residents will benefit from a shared roof garden with 360-degree views across the city and the Olympic park.
Work is planned to start next year and the mixed private and business property is expected to be ready sometime in 2010.
Control over the Thames Gateway regeneration project was recently handed to Joe Montgomery following the resignation of its chief executive, Judith Armitt.
The regeneration project will cost more than £9 billion and aims to build 160,000 new homes and create 225,000 jobs by 2011.